NARCAN Nasal Spray is an opioid antagonist indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression. (1)

NARCAN Nasal Spray is intended for immediate administration as emergency therapy in settings where opioids may be present. (1)

NARCAN Nasal Spray is not a substitute for emergency medical care. (1)

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NARCAN Nasal Spray is for intranasal use only. (2.1)

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Seek emergency medical care immediately after use. (2.1)

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Administration of a single spray of NARCAN Nasal Spray intranasally into one nostril. (2.2)

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Administer additional doses of NARCAN Nasal Spray, using a new nasal spray with each dose, if the patient does not respond or responds and then relapses into respiratory depression, additional doses of NARCAN Nasal Spray may be given every 2 to 3 minutes until emergency medical assistance arrives. (2.2)

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Additional supportive and/or resuscitative measures may be helpful while awaiting emergency medical assistance. (2.2)